Veterans administration cancer ensure program

In the absence of those molecules, K-Ras becomes hyperactive and emits continued signals telling cancer cells to divide. According to the research team, this is the first time an RNA molecule of this kind has been shown to act as a powerful tumor suppressor. The K-Ras mutation is an essential step in the development of nearly all human cancers.

Understanding how the two molecules block K-Ras activation may open new doors to blocking its function in cancer. Tobacco smoking as an etiologic factor in disease; cancer. Schrek R, Baker LA, et al. This seminal VA study linked smoking to cancer.

Cancer Res. The effect of direct cigarette smoke inhalation on the respiratory tree of dogs. This important paper explores the effects of smoking on the lungs. Natl Cancer Inst Monogr Jun; Transdermal administration of nicotine. This paper describes the value of the nicotine patch. Drug Alcohol Depend. Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group This VA study demonstrated the value of colonoscopies compared to sigmoidoscopy.

N Engl J Med Jul Wilt TJ. The PIVOT trial is a multicenter randomized controlled trial comparing radical prostatectomy with watchful waiting in men with prostate cancer. Age and race were associated with advanced neoplasia and colorectal cancer prevalence. Blacks had a higher overall prevalence of both, but not among screenings. J Clin Gastroenterol. Analysis of delayed surgical treatment and oncologic outcomes in clinical stage I non-small cell lung cancer. Surgical procedures delayed more than 12 weeks are associated with increased risk of recurrence and worse survival.

Time to colonoscopy after abnormal stool-based screening and risk for colorectal cancer incidence and mortality. Increased time to colonoscopy is associated with higher risk of colorectal cancer incidence, death, and late-stage colorectal cancer after abnormal fecal occult blood test or fecal immunochemical test.

Posttraumatic stress disorder and suicide among Veterans with prostate cancer. Patients with PTSD experienced greater suicide risk even after adjusting for important mediators.

Therapies for clinically localized prostate cancer: a comparative effectiveness review. Radical prostatectomy reduces mortality versus watchful waiting in clinically detected localized prostate cancer but causes more harms.

J Urol. Access to lung cancer screening in the Veterans Health Administration: does geographic distribution match need in the population? Disparities in lung cancer screening access exist based on where Veterans live, particularly for rural Veterans. Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models.

Time-restricted feeding is likely to be effective in breast cancer prevention and therapy. Nat Commun. Findings reveal simple, yet efficient, drug delivery approaches to overcome resistance often developed to pancreatic cancer.

Mol Pharm. African-American men with low-risk prostate cancer treated with radical prostatectomy in an equal-access health care system: implications for active surveillance. There was no significant difference in most adverse pathologic outcomes between African American and white patients. Prostate Cancer Prostatic Dis. Defects in long-chain 3-hydroxy acyl-CoA dehydrogenase lead to hepatocellular carcinoma: A novel etiology of hepatocellular carcinoma.

Mice with a deficiency of a protein analogous to HADHA were likely to develop nonalcoholic fatty liver disease when young.

Older mice with the protein deficiency developed hepatocellular carcinoma. Int J Cancer. Tobacco smoking and death from prostate cancer in US Veterans. Smoking at the time of diagnosis is associated with a higher risk of dying from prostate cancer as well as other causes of death. Survival of African American and non-Hispanic white men with prostate cancer in an equal-access health care system. African American men diagnosed with prostate cancer in the VA health system do not appear to present with more advanced disease or experience worse outcomes compared to non-Hispanic white men, in contrast to national trends, suggesting that access to care is an important determinant of racial equity.

Metformin is associated with reduced odds for colorectal cancer among persons with diabetes. Metformin was associated with reduced colorectal cancer odds—particularly rectal cancer—in a large sample of persons with diabetes undergoing colonoscopy. Clin Transl Gastroenterol. Clinical implementation of precision oncology is feasible across the VHA health care system, including rural sites. JCO Precis Oncol. End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography.

Artificial intelligence can outperform radiologists at diagnosing lung cancer. Nat Med. Impact of topical fluorouracil cream on costs of treating keratinocyte carcinoma nonmelanoma skin cancer and actinic keratosis.

Significant cost savings were found for patients treated with topical fluorouracil cream. J Am Acad Dermatol. Apalutamide treatment and metastasis-free survival in prostate cancer.

Among men with nonmetastatic castration-resistant prostate cancer, metastasis-free survival and time to symptomatic progression were significantly longer with apalutamide than with placebo. N Engl J Med. Delivering end-of-life cancer care: perspectives of providers. Specific strategies for cancer care redesign endorsed by health care providers may be used to create interventions that can more efficiently and effectively address gaps in end-of-life cancer care.

Am J Hosp Palliat Care. A conventional course of fluorouracil to the face and ears substantially reduces surgery for squamous cell carcinoma for 1 year. JAMA Dermatol. Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.

Polygenic hazard scores can be used for personalized genetic risk estimates that can predict for age at onset of aggressive prostate cancer. VA clinicians testing new radioactive tracer drug to track prostate cancer in the body. MVP study shows effectiveness of genetic screening tool for breast cancer risk. Genetic testing—the new standard in treatment for advanced prostate cancer. News , May 28, VA doctors are using artificial intelligence to diagnose cancer , Military Times , Feb.

Race disparity in U. Tobacco and Health , Department of Veterans Affairs. Cancer , Centers for Disease Control and Prevention.

Cancer , Nutrition. Cancer , HealthyPeople. Make an appointment. View all health services. Register for care. Richard L. Main phone: Mental health clinic: Refill and track your prescriptions. Send a secure message to your health care team. Metadata Updated: April 25, Non-public: This dataset is not for public access or use. Specific details are provided below. No file downloads are available because this is not a public dataset.

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